Determination of fibrinogen level in patients with type 2 diabetes mellitus in aboagla center for diabetes, Medani city, Sudan

Background: Diabetes Mellitus is a major leading health problem worldwide. DM type 2 is the most predominant type. High fibrinogen level in type 2 diabetes mellitus has been suggested to play a role in the occurrence of cardiovascular diseases in patients with type2 diabetes. Objective: The study aimed to determine the fibrinogen level in patients with type 2 diabetes mellitus. Methods: The study included fifty patients (cases) with type 2 diabetes mellitus and twenty are none diabetic (control group). The fibrinogen was compared in both group cases and control correlated by HbA1c and diabetes duration. Blood sample were collected into trisodium citrate container (2.5 ml) for fibrinogen estimation and EDITA container (2.5 ml)for HbA1c estimation. All sample investigated for fibrinogen using semi-automated technique. Data was analyzed using program SPSS. Result: The study revealed that plasma fibrinogen was significantly higher in type2 diabetic patients (cases) when compared to control group that showed statistically significance (P value .000) with significant correlation was found between plasma fibrinogen and HbA1c(P value .000) and none significant correlation was found between plasma fibrinogen and duration of diabetes (P value .411).