Effect of trigonella foenum seeds powder on lipids profile in fed rats

Twenty Wistar albino rats were divided into four groups named A, B, C and D of five rats each. Group A was given the basal diet and served as control, group B was given basal diet and 1% cholesterol added to the basal diet, group C was given basal diet and 1% cholesterol and 4% TSP added to the basal diet and group D was given basal diet and 1% cholesterol and 8% TSP added to the basal diet for four weeks. Blood samples were collected from all groups after four weeks. The level of total cholesterol and LDL-c was significantly (P› 0.05) decreased in group C and D compared to group B. while the level not significantly different in group C, and D compared to group B. the level of HDL-c were significantly (P› 0.05) decreased in group C and D compared to B. there was non- significant difference in the levels of total cholesterol, LDL-c, HDL-c and triglycerides in group C and D compared to the control group.