A case report of cutaneous cryptococcosis in a post renal transplant patient in a tertiary care hospital

Cryptococcosis is an opportunistic infection, caused by encapsulated fungi, belonging to genus Cryptococcus, it’s a fungus that lives in the environment which has the ability to cross Blood-Brain barrier .Cryptococcus neoformans is more commonly seen in immunocompromised individuals due to widespread use of Immunosuppressive therapy. A38 year old male patient with history of post renal transplant status was diagnosed with cutaneous cryptococcosis. Patient came to Nephrology OPD, Victoria hospital with complaints of non-healing ulcer over left buttock region with on and off fever for 3 months. Later patient was referred to Dermatology and Venerology department where he was examined and under aseptic precautions, biopsy was taken for histopathological examination and Tissue bits was sent for bacterial and fungal culture and sensitivity. The fungal culture report yielded Cryptococcus neoformans. Patient was started on IV amphotericin B for 2 weeks, later shifted on to oral drugs fluconazole and flucytosine at the time of discharge. Ulcer was completely healed by the end of 3 months, with no significant side effects. Cryptococcosis infection can spread to humans when they come in contact with pigeon droppings which usually occurs after inhalation of the fungal spores.