Comparative evaluation of antimicrobial efficacy of aqueous and ethanolic extract of salvadora persica with and without ultrasonic activation- an in vitro study

Aim: To compare the antimicrobial efficacy of alcoholic and aqueous extracts of Salvadora persica with and without ultrasonic activation against E.Feacalis. Materials and Methods: The samples were irrigated as follows after preparation upto size F3: Group 1: Experimental combination of 5% NaOCl and 40% S. persica Aqueous extract(n=10),Group 2: Experimental combination of 5% NaOCl and 40% S. persica Aqueous extract with ultrasonic activation (n=10), Group 3: Experimental combination of 5% NaOCl and 40% S. persica alcoholic extract (n=10),Group 4: Experimental combination of 5% NaOCl and 40% S. persica alcoholic extract with ultrasonic activation (n=10). Statistical Analysis: Antimicrobial efficacy – Independent T test and post hoc Mann–Whitney test. Results: Results shows that in the non-activation group, alcoholic extract of Salvadora persica performed better than the aqueous extract. In activation groups both aqueous and alcoholic extracts were found to perform similarly. Conclusion: Both alcoholic and aqueous extracts of Salvadora persica in combination with NaOCl had antimicrobial activity against E. Faecalis.Ultrasonic activation resulted in better reduction of CFU’s compared to non-activated groups for both aqueous and alcoholic extracts.