A comprehensive review of the versatile pumpkin seeds (Cucurbita maxima) as a valuable natural medicine

The seeds of Cucurbita maxima (pumpkin seeds) have been generally considered as agro-wastes and discarded inspite of having its high nutritional value as well as medicinal benefits. Pumpkin seeds contain high amount of protein, fatty acids, considerable amount of micronutrients like P, K, Mg, Mn and Ca. It is a good source of choline, an essential component for brain development. Pumpkin seed extracts and oils have been found useful in the treatment of Benign Prostatic Hyperplasia (BPH), parasite infestation, acrodermatitis enteropathica, hyperlipidemia, diabetes, depression to name a few. The observed benefits can attributed to the presence of bioactive components like phytosterols (eg, beta-sitosterol, stigmasterol), tocopherols, selenium (antioxidant), cucurbitin, squalene, lignan, and cardioprotective unsaturated fatty acids. Recent research has shone a light on the ever growing list of benefits of pumpkin seeds as a valuable food.