Nutrigenomics -the dietary approach to periodontal diseases-a review

Nutrigenomics is a branch of nutritional genomics focusing on identifying and understanding molecular- level interaction between nutrients and other dietary bio-actives with the genome. Nutrition is an important environmental factor that interacts with the genome to modulate disease risk. Genes are important in determining the function, but nutrition is able to modify the degree of gene expression. The response of an individual to dietary modification can be attributed to differences in their genetic make-up, which emphasizes the importance of exploring the role of nutrient–gene interactions in the development of chronic diseases and how diet affects the inflammatory mechanisms underlying severe periodontitis. Improved understanding of the mechanism behind periodontal tissue destruction, the potential protective role of nutrients and the advent of modern genomic measurement tools have led to an increased interest in the association between nutrition and periodontal disease. Nutrigenomics aims to reveal the relationship between nutrition and the genome and to provide the scientific basis for improved public health through dietary means. This manuscript reviews the interrelation between nutrigenomics and periodontal health.