Stem cells, a new age strategy for periodontal regeneration: a review

Stem cells are known for their ability of self-renewal and their potential of differentiation into mature cell types. These are present in almost all the multi-cellular organisms and are primitive cells. These cells have tremendous capacity for regeneration and can be utilized to repair as well as replace the demaged cells and can be used to transform the treatment options for cases like Parkinson’s disease, Alzheimer’s disease as well as for cancer and paralysis.If left untreated the periodontal disease can eventually lead to disease progression, leading to loss of tooth mainly in patients who are highly susceptible. Recently introduced Stem cells and tissue engineering have tremendous ability for treating the periodontal disease. After suitable stimulation, stem cells can differentiate into numerous cell types, possessing the regenerative potential. In cases of periodontal regeneration, MSCs provide the most promising results and have been tested in vitro as well as in vivo. Hence, this review discusses different stem cells, their uses as well as concise information on the stem cell based therapy used for the periodontal regeneration.